Human Galectin-9 Protein, His Tag
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产品编号
KMP2391
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别名
半乳糖凝集素, Galectin-9, Lgals9
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规格
- 50ug
- 100ug
- 200ug
| Catalog Number | KMP2391 |
| Alias | 半乳糖凝集素, Galectin-9, Lgals9 |
| Size | 50ug, 100ug, 200ug |
| Product Description | The Human Galectin-9 Protein(KMP2391) is produced in HEK293 Cells and the target gene encoding Met1-Thr323 is expressed with a 6His tag at the C-terminus. |
| Molecular Name | Galectin-9 |
| Product Introduction | Galectin-9:β-半乳糖苷结合凝集素,以分泌形式参与免疫细胞活化和功能调控。 |
| Molecular Weight | 36.19 kDa |
| Expression System | HEK293 Cells |
| Species | Human |
| Purity | >95% |
| SDS-PAGE | ![]() |
| Purification | Affinity Purification |
| Uniprot ID | O00182 |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Formulation | 50mM MOPS, 150mM NaCl, 1mM DTT, 1mM EDTA, 5% Trehalose, pH7.4 |
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
| Background | Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte(Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1. |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环,以保持蛋白的稳定性。
可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。
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