Human CD273 Protein, His Tag
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产品编号
KMP2388
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别名
程序性细胞死亡 1 配体 2, Programmed Cell Death 1 Ligand 2, CD273
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规格
- 50ug
- 100ug
- 200ug
| Catalog Number | KMP2388 |
| Alias | 程序性细胞死亡 1 配体 2, Programmed Cell Death 1 Ligand 2, CD273 |
| Size | 50ug, 100ug, 200ug |
| Product Description | The Human CD273 Protein(KMP2388) is produced in HEK293 Cells and the target gene encoding Leu20-Pro219 is expressed with a 6His tag at the C-terminus. |
| Molecular Name | CD273 |
| Product Introduction | CD273(PD-L2):免疫球蛋白超家族(IgSF)成员,以跨膜形式参与免疫细胞间的信号传导。 |
| Molecular Weight | 23.38 kDa |
| Expression System | HEK293 Cells |
| Species | Human |
| Purity | >95% |
| SDS-PAGE | ![]() |
| Purification | Affinity Purification |
| Uniprot ID | Q2LC89 |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Formulation | 20mM PB, 150mM NaCl, pH7.4 |
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
| Background | Programmed Cell Death 1 Ligand 2(PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环,以保持蛋白的稳定性。
可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。
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