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Human CD70 Protein, Fc Tag

Human CD70 Protein, Fc Tag

产品编号

KMP2377

别名

肿瘤坏死因子配体超家族成员 7, Tumor necrosis factor ligand superfamily member 7, CD70

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Catalog NumberKMP2377
Alias肿瘤坏死因子配体超家族成员 7, Tumor necrosis factor ligand superfamily member 7, CD70
Size50ug, 100ug, 200ug
Product DescriptionThe Human CD70 Protein(KMP2377) is produced in HEK293 Cells and the target gene encoding Gln45-Pro193 is expressed with a Fc tag at the C-terminus.
Molecular NameCD70
Product IntroductionCD70:TNF超家族II型跨膜蛋白,选择性表达于活化淋巴细胞,作为CD27配体参与免疫记忆形成。
Molecular Weight16.44 kDa
Expression SystemHEK293 Cells
SpeciesHuman
Purity>90%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDM0QZW2
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
FormulationPBS, pH7.4
Shipping ConditionIn general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
BackgroundCD27 Ligand(CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor(TNF) ligand family.Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Endotoxin<1.0 EU/ug determined by the LAL method
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
FAQ
  • 如何储存293F细胞中表达的蛋白?

    蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环,以保持蛋白的稳定性。

  • 如何提高293F细胞中的蛋白表达效率?

    可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。

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