Human FGL1 Protein, mFc Tag
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产品编号
KMP2360
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别名
纤维蛋白原样 1, Fibrinogen-like protein 1, FGL1
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规格
- 50ug
 - 100ug
 - 200ug
 
 
| Catalog Number | KMP2360 | 
| Alias | 纤维蛋白原样 1, Fibrinogen-like protein 1, FGL1 | 
| Size | 50ug, 100ug, 200ug | 
| Product Description | The Human FGL1 Protein(KMP2360) is produced in HEK293 Cells and the target gene encoding Leu23-Ile312 is expressed with a mFc tag at the C-terminus. | 
| Molecular Name | FGL1 | 
| Product Introduction | FGL1:分泌型纤维蛋白原样蛋白,主要由肝脏产生,参与组织修复和免疫调节过程。 | 
| Molecular Weight | 34.02 kDa | 
| Expression System | HEK293 Cells | 
| Species | Human | 
| Purity | >95% | 
| SDS-PAGE | ![]()  | 
| Purification | Affinity Purification | 
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. | 
| Formulation | PBS, 5% Trehalose, pH7.4 | 
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. | 
| Background | Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3. | 
| Endotoxin | <1.0 EU/ug determined by the LAL method | 
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 | 
可在纯化过程中加入蛋白酶抑制剂、低温操作,优化储存条件(如分装冻存于-80°C),并避免反复冻融。某些情况下,可选用蛋白酶缺陷型宿主菌减少降解风险。
常用SDS-PAGE、Western Blot检测表达,BCA/Bradford法测浓度,HPLC或质谱分析纯度,生物活性实验(如ELISA、酶活检测)验证功能。
							
							
							
							
						
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