Recombinant Mouse CD252 Protein, N-10*His tag_天津卡梅德科技发展有限公司

Recombinant Mouse CD252 Protein, N-10*His tag

产品编号

KMP2351

别名

肿瘤坏死因子受体超家族成员 4, Tumor necrosis factor ligand superfamily member 4, OX40L

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KMP2351
Alias	肿瘤坏死因子受体超家族成员 4, Tumor necrosis factor ligand superfamily member 4, OX40L
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	Recombinant Mouse OX40 Ligand is produced by our Mammalian expression system and the target gene encoding Ser51-Leu198 is expressed with a 8His tag at the N-terminus.
Molecular Name	CD252
Product Introduction	The Mouse CD252 Protein(KMP2351) is produced in HEK293 Cells and the target gene encoding 49-198 aa is expressed with a 10His tag at the N-terminus.
Molecular Weight	21-25 kDa
Expression System	HEK293F Cells
Species	Mouse
Concentration	联系销售经理获得最新批次的浓度
Purity	>95% as determined by SDS-PAGE
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	P43488
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	OX40 ligand(OX40L), also called CD252, is a single-pass type II membrane protein of the TNF/TNF receptor superfamily. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. OX40L–OX40 co-stimulation leads to activation of TNF receptor associated factor(TRAF) 2, 3 and 5. This pathway has been shown to prolong the survival of effector CD4+Th cells as well as contributes to generation of memory T cells.
Endotoxin	< 0.1 EU per ug
Protein Family	TNF superfamily, Type II transmembrane glycoprotein
Biological Activity	Measured by its ability to costimulate IL-2 secretion by mouse T cells in the presence of anti-CD3. The ED50 forthis effect is 10-30 ng/mL in the presence of a cross-linking antibody, Mouse AntipolyHistidine Monoclonal Antibody.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。