Cynomolgus CD252 Protein, His Tag
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产品编号
KMP2327
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别名
肿瘤坏死因子受体超家族成员 4, Tumor necrosis factor ligand superfamily member 4, OX40L
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规格
- 50ug
- 100ug
- 200ug
| Catalog Number | KMP2327 |
| Alias | 肿瘤坏死因子受体超家族成员 4, Tumor necrosis factor ligand superfamily member 4, OX40L |
| Size | 50ug, 100ug, 200ug |
| Product Description | The Cynomolgus CD252 Protein(KMP2327) is produced in HEK293 Cells and the target gene encoding Gln51-Leu183 is expressed with a 8His tag at the N-terminus. |
| Molecular Name | CD252 |
| Product Introduction | CD252(OX40L):TNF超家族成员,通过跨膜形式作为CD134(OX40)的配体参与T细胞活化。 |
| Molecular Weight | 14.63 kDa |
| Expression System | HEK293 Cells |
| Species | Cynomolgus |
| Purity | >95% |
| SDS-PAGE | ![]() |
| Purification | Affinity Purification |
| Uniprot ID | A0A1D5QQH7 |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Formulation | PBS, pH7.4 |
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
| Background | Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环,以保持蛋白的稳定性。
可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。
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