Mouse CD137L Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse CD137L Protein, His Tag

Mouse CD137L Protein, His Tag

产品编号

KMP2316

别名

肿瘤坏死因子配体超家族成员 9, CD137L, TNFSF9

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Catalog Number	KMP2316
Alias	肿瘤坏死因子配体超家族成员 9, CD137L, TNFSF9
Size	50ug, 100ug, 200ug
Product Description	The Mouse CD137L Protein(KMP2316) is produced in HEK293 Cells and the target gene encoding Arg104-Glu309 is expressed with a 10His tag at the N-terminus.
Molecular Name	CD137L
Product Introduction	CD137L（4-1BBL）：CD137的天然配体，通过跨膜形式参与免疫细胞活化和功能调节。
Molecular Weight	22.97 kDa
Expression System	HEK293 Cells
Species	Mouse
Purity	>90%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	P41274
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Formulation	PBS, pH7.4
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Background	Tumor necrosis factor ligand superfamily member 9, also known as 4-1BBL, is a member of the the tumor necrosis factor family. Mouse 4-1BBL cDNA encodes a 309 amino acid residues(aa) protein with an 82 aa N-terminal cytoplasmic domain, a 21 aa transmembrane domain and a 206 aa C-terminal extracellular domain. The extracellular domain of 4-1BBL has a tertiary structure similar to that of other TNFSF members, but shares only low aa sequence homology(14-16%). 4-1BBL is predominantly expressed on activated antigen presenting cells(APCs) such as B cells, macrophages and dendritic cells(DCs). It is also expressed on most T and B lymphoma cell lines. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.
Endotoxin	<1.0 EU/ug determined by the LAL method
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。

FAQ

如何储存293F细胞中表达的蛋白？

蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环，以保持蛋白的稳定性。
如何提高293F细胞中的蛋白表达效率？

可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。

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