Mouse CD48 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse CD48 Protein, His Tag

Mouse CD48 Protein, His Tag

产品编号

KMP2311

别名

信号传导淋巴细胞活化分子2, SLAM Family Member 2, CD48

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Catalog Number	KMP2311
Alias	信号传导淋巴细胞活化分子2, SLAM Family Member 2, CD48
Size	50ug, 100ug, 200ug
Product Description	The Mouse CD48 Protein(KMP2311) is produced in HEK293 Cells and the target gene encoding Phe23-Arg216 is expressed with a 6His tag at the C-terminus.
Molecular Name	CD48
Product Introduction	CD48：糖基磷脂酰肌醇（GPI）锚定蛋白，作为CD2的配体在淋巴细胞表面表达，参与免疫细胞间的黏附作用。
Molecular Weight	22 kDa
Expression System	HEK293 Cells
Species	Mouse
Purity	>95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q18PH8
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Formulation	PBS, pH7.4
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Background	CD48 is a GPI-linked protein in the CD2 family of immunoglobulin superfamily proteins. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. Among dendritic cells(DC), CD48 is selectively expressed on circulating myeloid DC and resident bone marrow and thymus DC. CD2, 2B4, and heparan sulfate function as CD48 ligands. CD48 is competent to transduce signals and can also trigger signaling through CD2 or 2B4. CD48 expressed on NK cells is coactivating, whereas CD48 expressed on other cell types inhibits NK cell activation.
Endotoxin	<1.0 EU/ug determined by the LAL method
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。

FAQ

如何储存293F细胞中表达的蛋白？

蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环，以保持蛋白的稳定性。
如何提高293F细胞中的蛋白表达效率？

可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。

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