Recombinant Human CD226 Protein, C-hFc and His tag
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产品编号
KMP2308
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别名
白细胞分化抗原, CD226 antigen, CD226
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMP2308 |
| Alias | 白细胞分化抗原, CD226 antigen, CD226 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Recombinant Human CD226 Antigen is produced by our Mammalian expression system and the target gene encoding Glu19-Asn247 is expressed with a 6His tag at the C-terminus. |
| Molecular Name | CD226 |
| Product Introduction | The Human CD226 Protein(KMP2308) is produced in HEK293 Cells and the target gene encoding Glu19-Asn247 is expressed with a 6His tag and Fc tag at the C-terminus. |
| Molecular Weight | 80-90 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | >95% as determined by SDS-PAGE |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | Q15762 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Human DNAX accessory molecule 1(DNAM-1/CD226) is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. Mature human DNAM-1 contains an extracellular domain(ECD) with two Ig-like C2-set domains and a cytoplasmic region that contains motifs for binding PDZ domains and band 4.1 family proteins. DNAM-1 is expressed on multiple lymphoid and myeloid cells and interacts with CD155 and CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, dendritic cell maturation, megakaryocyte and activated platelet adhesion to vascular endothelial cells, and monocyte extravasation; it inhibits the forrmation of osteoclasts. Plateletendothelium, interactions mediated by DNAM-1, enable the metastasis of tumor cells to the lung. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | TNF receptor superfamily |
| Biological Activity | Immobilized Recombinant Human CD226 at 2 μg/mL (100 μL/well) can bind Recombinant Human CD155 with a linearrange of 0.3-1.2 μg/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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