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Rhesus Macaque VTCN1 Protein

Rhesus Macaque VTCN1 Protein

产品编号

KMP2293

别名

含 V 组结构域的 T 细胞激活抑制剂 1, T cell costimulatory molecule B7x, VTCN1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias含 V 组结构域的 T 细胞激活抑制剂 1, T cell costimulatory molecule B7x, VTCN1
Catalog NumberKMP2293
Product DescriptionThe Rhesus Macaque VTCN1 Protein(KMP2293) is produced in HEK293 Cells and the target gene encoding Phe29-Ala258 is expressed.
Molecular NameVTCN1
SpeciesRhesus Macaque
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundB7 Homolog 4(B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells(Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
SDS-PAGE
Predicted Molecular Weight25.3 kDa
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot IDF7B770

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