Rhesus Macaque VTCN1 Protein_天津卡梅德科技发展有限公司

>>

>>

>>

>

Rhesus Macaque VTCN1 Protein

Rhesus Macaque VTCN1 Protein

产品编号

KMP2293

别名

含 V 组结构域的 T 细胞激活抑制剂 1, T cell costimulatory molecule B7x, VTCN1

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Catalog Number	KMP2293
Alias	含 V 组结构域的 T 细胞激活抑制剂 1, T cell costimulatory molecule B7x, VTCN1
Size	50ug, 100ug, 200ug
Product Description	The Rhesus Macaque VTCN1 Protein(KMP2293) is produced in HEK293 Cells and the target gene encoding Phe29-Ala258 is expressed.
Molecular Name	VTCN1
Product Introduction	VTCN1（B7-H4）：免疫球蛋白超家族跨膜蛋白，在抗原呈递细胞表面表达，参与T细胞活化的负调控。
Molecular Weight	25.3 kDa
Expression System	HEK293 Cells
Species	Rhesus Macaque
Purity	>95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	F7B770
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Formulation	PBS, pH7.4
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Background	B7 Homolog 4(B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells(Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
Endotoxin	<1.0 EU/ug determined by the LAL method
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。

FAQ

如何避免重组蛋白降解？

可在纯化过程中加入蛋白酶抑制剂、低温操作，优化储存条件（如分装冻存于-80°C），并避免反复冻融。某些情况下，可选用蛋白酶缺陷型宿主菌减少降解风险。
如何检测重组蛋白的表达和纯度？

常用SDS-PAGE、Western Blot检测表达，BCA/Bradford法测浓度，HPLC或质谱分析纯度，生物活性实验（如ELISA、酶活检测）验证功能。

推荐产品

400-621-6806
18630936064（微信同号）
周一至周五 8:30-18:00
0