Rhesus Macaque CD160 Protein, Fc Tag_天津卡梅德科技发展有限公司

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Rhesus Macaque CD160 Protein, Fc Tag

Rhesus Macaque CD160 Protein, Fc Tag

产品编号

KMP2292

别名

自然杀伤细胞受体BY55, CD160 antigen, CD160

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Catalog Number	KMP2292
Alias	自然杀伤细胞受体BY55, CD160 antigen, CD160
Size	50ug, 100ug, 200ug
Product Description	The Rhesus Macaque CD160 Protein(KMP2292) is produced in HEK293 Cells and the target gene encoding Met1-Leu158 is expressed with a Fc tag at the C-terminus.
Molecular Name	CD160
Product Introduction	CD160：免疫球蛋白超家族（IgSF）糖蛋白，以GPI锚定或跨膜形式表达于NK细胞毒性亚群，通过特异性配体结合参与免疫信号传导。
Molecular Weight	17.38 kDa
Expression System	HEK293 Cells
Species	Rhesus Macaque
Purity	>95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	G7MG20
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Formulation	PBS, pH7.4
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Background	CD160 antigen is a cell membrane protein which contains one Ig-likeV-type(immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and smal lintestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.
Endotoxin	<1.0 EU/ug determined by the LAL method
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。

FAQ

如何提高重组蛋白的可溶性表达？

可优化表达条件（如降低诱导温度、调整IPTG浓度）、使用促溶标签（如SUMO、GST）、共表达分子伴侣，或尝试不同宿主系统（如哺乳动物细胞或昆虫细胞）以提高可溶性蛋白产量。
重组蛋白纯化常用的方法有哪些？

常用的纯化方法包括亲和层析（如His-Tag、GST-Tag）、离子交换层析、疏水相互作用层析（HIC）和凝胶过滤层析。具体方法取决于蛋白特性和标签类型。

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