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Human CD273 Protein, His Tag, Avi Tag

Human CD273 Protein, His Tag, Avi Tag

产品编号

KMP2276

别名

程序性细胞死亡 1 配体 2, Programmed Cell Death 1 Ligand 2, CD273

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias程序性细胞死亡 1 配体 2, Programmed Cell Death 1 Ligand 2, CD273
Catalog NumberKMP2276
Product DescriptionThe Human CD273 Protein(KMP2276) is produced in HEK293 Cells and the target gene encoding Leu20-Pro219 is expressed with a 6His, Avi tag at the C-terminus.
Molecular NameCD273
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM PB, 150mM NaCl, pH7.4
BackgroundProgrammed Cell Death 1 Ligand 2(PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
SDS-PAGE
Predicted Molecular Weight23.38 kDa
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot IDQ9BQ51
FunctionInvolved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).

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