Recombinant Human FGL1 Protein, Fc Tag
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产品编号
KMP2258
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别名
纤维蛋白原样 1, Fibrinogen-like protein 1, FGL1
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMP2258 |
| Alias | 纤维蛋白原样 1, Fibrinogen-like protein 1, FGL1 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | The Human FGL1 Protein(KMP2258) is produced in HEK293 Cells and the target gene encoding (Leu23-Ile312) is expressed with a Fc tag at the N-terminus. |
| Molecular Name | FGL1 |
| Product Introduction | 纤维蛋白原样蛋白1 (FGL1) 是纤维蛋白原相关蛋白家族的成员。它在免疫调节和组织修复中发挥重要作用。FGL1与肝功能和炎症相关，并已被证明可作为免疫检查点调节剂，尤其是在慢性疾病和癌症的背景下促进免疫耐受。 |
| Molecular Weight | 60-65 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | >93% as determined by SDS-PAGE |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | Q08830 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Fibrinogen-like protein family |
| Biological Activity | Immobilized recombinant Human FGL1 at 5 μg/mL (100 μL/well) can bind recombinant Human LAG3 with a linearrange of 0.5-21.6 ng/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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