Human TNFRSF17 Protein, Fc Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human TNFRSF17 Protein, Fc Tag, Avi Tag

Human TNFRSF17 Protein, Fc Tag, Avi Tag

产品编号

KMP2254

别名

B细胞成熟抗原, CD269, BCMA

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Catalog Number	KMP2254
Alias	B细胞成熟抗原, CD269, BCMA
Size	50ug, 100ug, 200ug
Product Description	The Human TNFRSF17 Protein(KMP2254) is produced in HEK293 Cells and the target gene encoding Met1-Ala54 is expressed with a Fc, Avi tag at the C-terminus.
Molecular Name	TNFRSF17
Product Introduction	TNFRSF17（BCMA）：TNF受体超家族跨膜蛋白，主要表达于浆细胞，参与B细胞成熟调控。
Molecular Weight	5.9 kDa
Expression System	HEK293 Cells
Species	Human
Purity	>90%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q6PE46
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Formulation	PBS, pH7.4
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Background	B cell maturation protein(BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily(TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid(aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.
Endotoxin	<1.0 EU/ug determined by the LAL method
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。

FAQ

如何避免重组蛋白降解？

可在纯化过程中加入蛋白酶抑制剂、低温操作，优化储存条件（如分装冻存于-80°C），并避免反复冻融。某些情况下，可选用蛋白酶缺陷型宿主菌减少降解风险。
如何检测重组蛋白的表达和纯度？

常用SDS-PAGE、Western Blot检测表达，BCA/Bradford法测浓度，HPLC或质谱分析纯度，生物活性实验（如ELISA、酶活检测）验证功能。

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