Human 5T4 Protein, Avi Tag, His Tag
- 
									
产品编号
KMP2244
 - 
									
别名
滋养层糖蛋白, Human M6P1 Protein, 5T4
 - 
									
规格
- 50ug
 - 100ug
 - 200ug
 
 
| Catalog Number | KMP2244 | 
| Alias | 滋养层糖蛋白, Human M6P1 Protein, 5T4 | 
| Size | 50ug, 100ug, 200ug | 
| Product Description | The Human 5T4 Protein(KMP2244) is produced in HEK293 Cells and the target gene encoding Ser32-Ser355 is expressed with a AVI, 6His tag at the C-terminus. | 
| Molecular Name | 5T4 | 
| Product Introduction | 5T4(TPBG):一种免疫球蛋白超家族(IgSF)糖蛋白,在胚胎发育和组织再生过程中发挥重要作用,参与细胞间相互作用和信号传导。 | 
| Molecular Weight | 36.15 kDa | 
| Expression System | HEK293 Cells | 
| Species | Human | 
| Purity | >95% | 
| SDS-PAGE | ![]()  | 
| Purification | Affinity Purification | 
| Uniprot ID | Q13641 | 
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. | 
| Formulation | PBS, pH7.4 | 
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. | 
| Background | Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap(LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. | 
| Endotoxin | <1.0 EU/ug determined by the LAL method | 
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 | 
蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环,以保持蛋白的稳定性。
可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。
							
							
							
							
						
								0