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Recombinant Human CD96 Protein, His Tag

Recombinant Human CD96 Protein, His Tag

产品编号

KMP2242

别名

T细胞表面蛋白触觉, T-cell surface protein tactile, CD96

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMP2242
AliasT细胞表面蛋白触觉, T-cell surface protein tactile, CD96
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionRecombinant Human T-cell Surface Protein Tactile is produced by our Mammalian expression system and the target gene encoding Val22-Met503 is expressed with a Fc tag at the C-terminus.
Molecular NameCD96
Product IntroductionCD96,又称T细胞免疫球蛋白和黏蛋白结构域分子3 (TIM-3),是一种参与免疫调节和T细胞耗竭的受体。
Molecular Weight55 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity>95% as determined by SDS-PAGE
SDS-PAGE
PurificationAffinity Purification
Uniprot IDP40200-2
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundThe cluster of differentiation(CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor(PVR), anectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells.
Endotoxin< 0.1 EU per ug
Protein FamilyImmunoglobulin superfamily (IgSF)
Biological ActivityImmobilized Human CD155/PVR hFc at 2 μg/ml (100 μl/well) can bind Human CD96 His, the EC50 of Human CD96 His is 200-800 ng/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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