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Cynomolgus TNFRSF17 Protein, His Tag

Cynomolgus TNFRSF17 Protein, His Tag

产品编号

KMP2241

别名

B细胞成熟抗原, CD269, BCMA

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Catalog NumberKMP2241
AliasB细胞成熟抗原, CD269, BCMA
Size50ug, 100ug, 200ug
Product DescriptionThe Cynomolgus TNFRSF17 Protein(KMP2241) is produced in HEK293 Cells and the target gene encoding Met1-Ala53 is expressed with a 6His tag at the C-terminus.
Molecular NameTNFRSF17
Product IntroductionTNFRSF17(BCMA):TNF受体超家族跨膜蛋白,主要表达于浆细胞,参与B细胞成熟调控。
Molecular Weight6.49 kDa
Expression SystemHEK293 Cells
SpeciesCynomolgus
Purity>85%
PurificationAffinity Purification
Uniprot IDA0A2K5UD97
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Formulation50mM Tris, 100mM Glycine, pH7.5
Shipping ConditionIn general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
BackgroundB cell maturation antigen(BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development,function and regulation.
Endotoxin<1.0 EU/ug determined by the LAL method
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
FAQ
  • 如何储存293F细胞中表达的蛋白?:蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环,以保持蛋白的稳定性。

  • 如何提高293F细胞中的蛋白表达效率?:可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。

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