Recombinant Human CNDP1 Protein, C-10*His tag
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产品编号
KMH896
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别名
C末端去氨基化酶1, CN1, CPGL2, HsT2308, carnosine dipeptidase 1
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH896 |
| Alias | C末端去氨基化酶1, CN1, CPGL2, HsT2308, carnosine dipeptidase 1 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH896 Recombinant Human CNDP1 Protein, C-10*His tag contains the human CNDP1(28-507 aa) was expressed in Mammalian cells. |
| Molecular Name | CNDP1 |
| Product Introduction | CNDP1 (KMH896) 参与胰岛素敏感性的调节，并与糖尿病的发生发展相关。 |
| Molecular Weight | 65 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | Q96KN2 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | CNDP1, also known as beta-Ala-His dipeptidase, belongs to the peptidase M2A family. The shortest allelic form (CNDP1 Mannheim) was more common in the absence of nephropathy and was associated with lower serum carnosinase levels. Carnosine inhibited the increased production of fibronectin and collagen type VI in podocytes and the increased production of TGF-beta in mesangial cells. Diabetic patients with the CNDP1 Mannheim variant are less susceptible for nephropathy. Carnosine protects against the adverse effects of high glucose levels on renal cells. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Measured by its ability to cleave carnosine ( beta -Ala-L-His) in a two-step assay. The specific activity is >250 pmol/min/µg, as measured under the described conditions. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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