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Recombinant Human CNDP1 Protein, His Tag

Recombinant Human CNDP1 Protein, His Tag

产品编号

KMH896

别名

CN1, CPGL2, HsT2308, carnosine dipeptidase 1

规格
  • 50ug
  • 100ug
产品介绍
AliasCN1, CPGL2, HsT2308, carnosine dipeptidase 1
Catalog NumberKMH896
Molecular NameCNDP1
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundCNDP1, also known as beta-Ala-His dipeptidase, belongs to the peptidase M2A family. The shortest allelic form (CNDP1 Mannheim) was more common in the absence of nephropathy and was associated with lower serum carnosinase levels. Carnosine inhibited the increased production of fibronectin and collagen type VI in podocytes and the increased production of TGF-beta in mesangial cells. Diabetic patients with the CNDP1 Mannheim variant are less susceptible for nephropathy. Carnosine protects against the adverse effects of high glucose levels on renal cells.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight52.91 kDa
Note仅供科研使用

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