Recombinant Human BTN1A1 Protein, C-His tag
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产品编号
KMH762
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别名
BTN1A1, BT, BTN, BTN1, butyrophilin subfamily 1 member A1
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH762 |
| Alias | BTN1A1, BT, BTN, BTN1, butyrophilin subfamily 1 member A1 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH762 Recombinant Human BTN1A1 Protein, C-His tag contains the human BTN1A1(27-242aa) was expressed in Mammalian cells. |
| Molecular Name | BTN1A1 |
| Product Introduction | (KMH762) BTN1A1作为一种免疫抑制蛋白，调节免疫系统的功能。 |
| Molecular Weight | 33-38 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | Q13410 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | BTK (also known as Bruton tyrosine kinase) plays a crucial role in B-lymphocyte differentiation and activation. BTK interacts with SRC homology 3 domains of FYN, LYN and HCK that are activated upon stimulation of B- and T-cell receptors. Defects in the BTK gene cause Agammaglobulinemia, an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. The unique role of BTK makes it a desirable target for potential anti-cancer, anti-inflammatory and anti-viral agents as well as other treatments. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Measured by its ability to inhibit Anti-CD3-induced proliferation of jurkat cells. The ED50 for this effect is 3.35-13.4 ng/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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如何判断蛋白是否有抗体反应性？
可以使用ELISA、Western blot或免疫沉淀等技术来检测蛋白与特定抗体的结合反应性。
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如何避免蛋白在纯化过程中的损失？
使用温和的纯化条件、优化缓冲液成分和减少操作步骤，可以有效减少蛋白的损失。
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