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Recombinant Human BTLA Protein, C-hFc and His tag

Recombinant Human BTLA Protein, C-hFc and His tag

产品编号

KMH760

别名

BTLA受体BTLA1, CD272, B and T lymphocyte associated

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH760
AliasBTLA受体BTLA1, CD272, B and T lymphocyte associated
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH760 Recombinant Human BTLA Protein, C-hFc and His tag contains the human BTLA(Lys31-Thr134) was expressed in Mammalian cells.
Molecular NameBTLA
Product Introduction (KMH760) BTLA是免疫检查点分子,调节免疫耐受和免疫逃逸。
Molecular Weight50-60 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDQ7Z6A9-2
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundBTK (also known as Bruton tyrosine kinase) plays a crucial role in B-lymphocyte differentiation and activation. BTK interacts with SRC homology 3 domains of FYN, LYN and HCK that are activated upon stimulation of B- and T-cell receptors. Defects in the BTK gene cause Agammaglobulinemia, an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. The unique role of BTK makes it a desirable target for potential anti-cancer, anti-inflammatory and anti-viral agents as well as other treatments.
Endotoxin< 0.1 EU per ug
Protein FamilyOther protein
Biological ActivityImmobilized Recombinant human BTLA at 3 μg/mL (100 μL/well) can bind Biotinylated Recombinant human HVEM with a linearrange of 18-72 ng/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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