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Recombinant Human ANTXR1 Protein, C-His tag

Recombinant Human ANTXR1 Protein, C-His tag

产品编号

KMH675

别名

抗毒素受体1, ATR, GAPO, TEM8, ANTXR cell adhesion molecule 1

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH675
Alias抗毒素受体1, ATR, GAPO, TEM8, ANTXR cell adhesion molecule 1
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH675 Recombinant Human ANTXR1 Protein, C-His tag contains the human ANTXR1(33-321 aa) was expressed in Mammalian cells.
Molecular NameANTXR1
Product IntroductionANTXR1 (KMH675) 在细胞迁移、发育和免疫反应中起到重要作用。
Molecular Weight38-46 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDQ9H6X2
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundAnthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI).
Endotoxin< 0.1 EU per ug
Protein FamilyOther protein
Biological ActivityMeasured by its binding ability in a functional ELISA. When Anthrax Protective Antigen is coated at 1.5 μg/mL (100 μL/well), the concentration of Recombinant Human TEM8/ANTXR1 that produces 50% optimal binding response is 0.6-3.6 μg/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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