Recombinant Human ANTXR1 Protein, C-His tag
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产品编号
KMH675
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别名
抗毒素受体1, ATR, GAPO, TEM8, ANTXR cell adhesion molecule 1
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
| Catalog Number | KMH675 |
| Alias | 抗毒素受体1, ATR, GAPO, TEM8, ANTXR cell adhesion molecule 1 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH675 Recombinant Human ANTXR1 Protein, C-His tag contains the human ANTXR1(33-321 aa) was expressed in Mammalian cells. |
| Molecular Name | ANTXR1 |
| Product Introduction | ANTXR1 (KMH675) 在细胞迁移、发育和免疫反应中起到重要作用。 |
| Molecular Weight | 38-46 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | ![]() |
| Purification | Affinity Purification |
| Uniprot ID | Q9H6X2 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI). |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Measured by its binding ability in a functional ELISA. When Anthrax Protective Antigen is coated at 1.5 μg/mL (100 μL/well), the concentration of Recombinant Human TEM8/ANTXR1 that produces 50% optimal binding response is 0.6-3.6 μg/mL. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
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