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Recombinant Human ACVR2B C-fc Protein, C-hFc and His tag

Recombinant Human ACVR2B C-fc Protein, C-hFc and His tag

产品编号

KMH633

别名

ACVR2B受体HTX4, ACTRIIB, ActR IIB, activin A receptor type 2B

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH633
AliasACVR2B受体HTX4, ACTRIIB, ActR IIB, activin A receptor type 2B
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH633 Recombinant Human ACVR2B C-fc Protein, C-hFc and His tag contains the human ACVR2B(19-134 aa) was expressed in Mammalian cells.
Molecular NameACVR2B
Product Introduction (KMH633) ACVR2B在肌肉生长和组织发育过程中起到调节作用。
Molecular Weight60 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDQ13705
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundACVR2B or activin A receptor, type IIB is belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins that signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. ACVR2B is help to regulate muscle growth. ACVR2B is a transmembrane protein that composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity.
Endotoxin< 0.1 EU per ug
Protein FamilyOther protein
Biological ActivityMeasured by its ability to inhibit Activin Ainduced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Approximately 0.3-1 µg/mL of rhActivin RIIB/Fc Chimera will inhibit 50% of the biological response due to 3 ng/mL ofrhActivin A.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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