Recombinant Human Activin RIB/ALK-4/ACVR1B Protein, C-hFc and His tag
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产品编号
KMH628
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别名
ACVR1B受体, ALK4, SKR2, ACTRIB, ACVRLK4, activin A receptor type 1B
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH628 |
| Alias | ACVR1B受体, ALK4, SKR2, ACTRIB, ACVRLK4, activin A receptor type 1B |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH628 Recombinant Human Activin RIB/ALK-4/ACVR1B Protein, C-hFc and His tag contains the human ACVR1B(32-126 aa) was expressed in Mammalian cells. |
| Molecular Name | ACVR1B |
| Product Introduction | (KMH628) ACVR1B是调节细胞增殖和分化的受体，参与胚胎发育。 |
| Molecular Weight | 45-50 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| Purification | Affinity Purification |
| Uniprot ID | P36896 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Activin RIB, also known as ALK4, is a glycosylated type I receptor in the superfamily of TGF-β serine/threonine kinase receptors. Activin RIB associates with Activin RIIB to form a receptor complex for activin and inhibin molecules. These ligands bind to Activin RIIB which then associates with and phosphorylates the cytoplasmic domain of Activin RIB to initiate signal transduction.Within the ECD, human Activin RIB shares 93% and 95% aa sequence identity with mouse and rat Activin RIB, respectively. It shares 25% - 35% aa sequence identity with other human type I receptors Activin RIA, Activin RIC, BMPR-IA, BMPR-IB, and TGF-β R1. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized rhActivin RIB/Fc Chimera at 2 µg/mL (100 µL/well) can bind rhCripto with a linearrange of 0.8-100 ng/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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