Recombinant Human HMGB1 Protein, C-His tag_天津卡梅德科技发展有限公司

Recombinant Human HMGB1 Protein, C-His tag

产品编号

KMH574

别名

高迁移率族蛋白B1, HMG1, HMG3, HMG 1, SBP 1, high mobility group box 1

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KMH574
Alias	高迁移率族蛋白B1, HMG1, HMG3, HMG 1, SBP 1, high mobility group box 1
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	KMH574 Recombinant Human HMGB1 Protein, C-His tag contains the human HMGB1(Met1-Glu215) was expressed in Mammalian cells.
Molecular Name	HMGB1
Product Introduction	HMGB1 (KMH574) 是一种核糖核酸结合蛋白，参与细胞凋亡、免疫反应和组织修复。
Molecular Weight	30 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	P09429
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	Supplied as solution form in 50mM Tris HCl pH 7, 150mM NaCl, 1mM EDTA./ Lyophilized from 50mM Tris HCl pH 7, 150mM NaCl, 1mM EDTA.
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	High-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 3 kDa, 215 amino acid (aa) single chain polypeptide containing three domains: two N-terminal globular, 7 aa positively charged DNA-binding domains (HMG boxes A and B), and a negatively charged 3 aa C-terminal region that contains only Asp and Glu.4, 5 Residues 27 - 43 and 178 - 184 contain a NLS. Posttranslational modifications of the molecule have been reported, with acetylation occurring on as many as 17 lysine residues.
Endotoxin	< 0.1 EU per ug
Protein Family	Other protein
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized Human HMGB1 at 2μg/mL (100 μL/well) can bind Human AGER/RAGE with a linear range of 0.1-42.8 ng/mL.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。