Recombinant Human B-Gal/GLB1 Protein, C-His tag
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产品编号
KMH541
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别名
β-半乳糖苷酶, EBP, ELNR1, MPS4B, galactosidase beta 1
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH541 |
| Alias | β-半乳糖苷酶, EBP, ELNR1, MPS4B, galactosidase beta 1 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH541 Recombinant Human B-Gal/GLB1 Protein, C-His tag contains the human GLB1(1-677 aa) was expressed in Mammalian cells. |
| Molecular Name | GLB1 |
| Product Introduction | GLB1 (KMH541) 参与糖类代谢，影响细胞内的糖代谢过程。 |
| Molecular Weight | 70-95 kDa |
| Expression System | CHO Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | P16278 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS, pH7.5 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Galactosidase is a lysosomal Galactosidase that hydrolyzes the terminal Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex . An alternative splicing at the RNA level of Galactosidase results a catalytically inactive Galactosidase that plays an important role in vascular development. Defects of galactosidase (GLB1) are the cause of diseases like GM1-gangliosidosis which is a lysosomal storage disease and Morquio Syndrome B that cause patients to have abnormal elastic fibers. More than 1 mutations have been identified for Galactosidase, which result in different residual activities of the mutant enzymes and a spectrum of symptoms in the two related diseases. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Measured by its ability to cleave a fluorogenic substrate, 4- Methylumbelliferylbeta -Dgalactopyranoside. The specific activity is >1,800 pmol/min/μg, as measured underthe described conditions. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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