Recombinant Human B2M Protein, C-His tag
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产品编号
KMH539
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别名
B2M蛋白, IMD43, beta 2 microglobulin
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH539 |
| Alias | B2M蛋白, IMD43, beta 2 microglobulin |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH539 Recombinant Human B2M Protein, C-His tag contains the human B2M(21-119 aa) was expressed in Mammalian cells. |
| Molecular Name | B2M |
| Product Introduction | (KMH539) B2M是主要的免疫分子，在MHC I类分子中发挥重要作用，参与抗原呈递。 |
| Molecular Weight | 13 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | P61769 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied as solution form in 150mM NaCl, 50mM Tris-HCl, pH 8.0./ Lyophilized from 150mM NaCl, 50mM Tris-HCl, pH 8.0. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Beta-2-microglobulin (B2M), is a component of MHC class I molecules which belongs to the beta-2-microglobulin family. B2M is present on all nucleated cells (excludes red blood cells). B2M associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa. An additional function of B2M is association with the HFE protein, together regulating the expression of hepcidin in the liver which targets the iron transporter ferroportin on the cytoplasmic membrane of enterocytes and macrophages for degradation resulting in decreased iron uptake from food and iron release from recycled red blood cells respectively. Loss of this function causes iron excess and hemochromatosis. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP). |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Immobilized Recombinant Human B2M at 2 μg/mL (100 μL/well) can bind Recombinant Human CD8 alpha with a linearrange of 30-350 ng/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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已表达的蛋白能否用于疫苗开发？
是的，重组蛋白可以用于疫苗的开发，特别是在生产抗原性蛋白和研究免疫反应方面。
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- 电话：400-621-6806
- 手机：13116038708
- 邮箱：info@kmdbioscience.com
- 地址：天津市武清区国际企业社区A5栋
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400-621-6806 -
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