Recombinant Human FOLR1 Protein, C-His tag_天津卡梅德科技发展有限公司

Recombinant Human FOLR1 Protein, C-His tag

产品编号

KMH528

别名

叶酸受体1, FBP, FOLR, FRalpha, folate receptor alpha

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Catalog Number	KMH528
Alias	叶酸受体1, FBP, FOLR, FRalpha, folate receptor alpha
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	KMH528 Recombinant Human FOLR1 Protein, C-His tag contains the human FOLR1(25-233 aa) was expressed in Mammalian cells.
Molecular Name	FOLR1
Product Introduction	FOLR1 (KMH528) 叶酸的受体，参与叶酸的吸收，影响细胞的DNA合成。
Molecular Weight	35-40 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	P15328
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Folate Receptor 1 (FOLR1) is also known as Folate receptor alpha, Folate Binding Protein (FBP), FOLR, and is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Mature FOLR1 is an N-glycosylated protein that is anchored to the cell surface by a GPI linkage. FOLR1 is predominantly expressed on epithelial cells and is dramatically upregulated on many carcinomas. FOLR1 is internalized to the endosomal system where it dissociates from its ligand before recycling to the cell surface. A soluble form of FOLR1 can be proteolytically shed from the cell surface into the serum and breast milk. Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD). NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life.
Endotoxin	< 0.1 EU per ug
Protein Family	Biomarker
Biological Activity	Immobilized Human FOLR1 at 1 μg/mL (100 μL/well) can bind FOLR1 Antibody with a linearrange of 0.2-1 ng/mL
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。