Recombinant Human ICOSLG Protein, C-His tag
-
产品编号
KMH512
-
别名
ICOS配体, B7h, B7H2, GL50, B7 H2, B7RP1, CD275, ICOSL, LICOS, B7RP 1, ICOS L, inducible T cell costimulator ligand
-
规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
| Catalog Number | KMH512 |
| Alias | ICOS配体, B7h, B7H2, GL50, B7 H2, B7RP1, CD275, ICOSL, LICOS, B7RP 1, ICOS L, inducible T cell costimulator ligand |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH512 Recombinant Human ICOSLG Protein, C-His tag contains the human ICOSLG(Asp19-Ser258) was expressed in Mammalian cells. |
| Molecular Name | ICOSLG |
| Product Introduction | ICOSLG (KMH512) 是免疫系统中的配体,参与免疫细胞的活化与调节。 |
| Molecular Weight | 45-67 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | ![]() |
| Purification | Affinity Purification |
| Uniprot ID | O75144 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS, pH7.5 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | B7H2 is ligand for the T-cell specific cell surface receptor ICOS and acts as a costimulatory signal for T-cell proliferation and differentiation. It induces also B-cell proliferation and differentiation in plasma cells. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Antibody drug target protein |
| Biological Activity | Immobilized Human ICOSLG at 1 μg/mL (100 μL/well) can bind Human ICOS/CD278 with a linear range of 2- 15 ng/mL. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
是的,293F细胞可以共表达多种蛋白,但可能需要优化共转染条件(如质粒比例、转染条件)以获得高表达水平。
常见问题包括低蛋白产量、蛋白折叠不良、聚集和蛋白降解。通过优化转染条件和蛋白纯化方案可以解决这些问题。
0