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Recombinant Human TNF Protein, His Tag

Recombinant Human TNF Protein, His Tag

产品编号

KMH494

别名

DIF, TNFA, TNFSF2, TNLG1F, TNF alpha, tumor necrosis factor

规格
  • 50ug
  • 100ug
产品介绍
AliasDIF, TNFA, TNFSF2, TNLG1F, TNF alpha, tumor necrosis factor
Catalog NumberKMH494
Molecular NameTNF
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyAntibody drug target protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationSupplied as solution form in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl./Lyophilized from 50 mM Tris-HCl, pH 7.5, 150 mM NaCl.
BackgroundTnf is secreted bymacrophages, monocytes, neutrophils, T-cells, NK- cells following theirstimulation by bacterial lipopolysaccharides. Cells expressing CD4 secrete TNF-alpha while CD8(+) cells secrete little or no TNF- alpha. Stimulatedperipheral neutrophilic granulocytes but also unstimulated cells and also anumber of transformed cell lines, astrocytes, microglial cells, smooth musclecells, and fibroblasts also secrete Tnf. Human milk also contains thisfactor. The synthesis of TNF-alpha is induced by many different stimuliincluding interferons, IL2, GM-CSF, SP, Bradykinin, Immune complexes, inhibitors of cyclooxygenase and PAF (platelet activating factor).
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight17.32 kDa
Note仅供科研使用

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