Recombinant Human TNF Protein, His Tag
-
产品编号
KMH494
-
别名
DIF, TNFA, TNFSF2, TNLG1F, TNF alpha, tumor necrosis factor
-
规格
- 50ug
- 100ug
Alias | DIF, TNFA, TNFSF2, TNLG1F, TNF alpha, tumor necrosis factor |
Catalog Number | KMH494 |
Molecular Name | TNF |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Antibody drug target protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | Supplied as solution form in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl./Lyophilized from 50 mM Tris-HCl, pH 7.5, 150 mM NaCl. |
Background | Tnf is secreted bymacrophages, monocytes, neutrophils, T-cells, NK- cells following theirstimulation by bacterial lipopolysaccharides. Cells expressing CD4 secrete TNF-alpha while CD8(+) cells secrete little or no TNF- alpha. Stimulatedperipheral neutrophilic granulocytes but also unstimulated cells and also anumber of transformed cell lines, astrocytes, microglial cells, smooth musclecells, and fibroblasts also secrete Tnf. Human milk also contains thisfactor. The synthesis of TNF-alpha is induced by many different stimuliincluding interferons, IL2, GM-CSF, SP, Bradykinin, Immune complexes, inhibitors of cyclooxygenase and PAF (platelet activating factor). |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 17.32 kDa |
Note | 仅供科研使用 |