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Recombinant Human CD360/IL21R Protein, His Tag

Recombinant Human CD360/IL21R Protein, His Tag

产品编号

KMH492

别名

NILR, CD360, IMD56, interleukin 21 receptor

规格
  • 50ug
  • 100ug
产品介绍
AliasNILR, CD360, IMD56, interleukin 21 receptor
Catalog NumberKMH492
Molecular NameIL21R
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundInterleukin 21 Receptor belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight25.96 kDa
Note仅供科研使用

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