Recombinant Human CD360/IL21R Protein, C-His tag
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产品编号
KMH492
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别名
IL21受体, NILR, CD360, IMD56, interleukin 21 receptor
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规格
- 20ug
 - 50ug
 - 100ug
 - 200ug
 - 1mg
 
 
| Catalog Number | KMH492 | 
| Alias | IL21受体, NILR, CD360, IMD56, interleukin 21 receptor | 
| Size | 20ug, 50ug, 100ug, 200ug, 1mg | 
| Product Description | KMH492 Recombinant Human CD360/IL21R Protein, C-His tag contains the human IL21R(20-236 aa) was expressed in Mammalian cells. | 
| Molecular Name | IL21R | 
| Product Introduction | IL21R (KMH492) 是IL21的受体,调节T细胞和B细胞的功能,参与免疫反应。 | 
| Molecular Weight | 40-50 kDa | 
| Expression System | HEK293F Cells | 
| Species | Human | 
| Concentration | 联系销售经理获得最新批次的浓度 | 
| Purity | ≥92% | 
| SDS-PAGE | ![]()  | 
| Purification | Affinity Purification | 
| Uniprot ID | Q9HBE5 | 
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. | 
| Formulation | PBS | 
| Shipping Condition | This product is shipped on ice packs or dry ice. | 
| Background | Interleukin 21 Receptor belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described. | 
| Endotoxin | < 0.1 EU per ug | 
| Protein Family | CD molecule | 
| Biological Activity | Immobilized Recombinant Human IL21R at 2 μg/mL (100 μL/well) can bind Recombinant Human IL-21 with a linearrange of 0.128-5.63 ng/mL. | 
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 | 
							
							
							
							
						
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