Recombinant Human CD358/TNFRSF21 Protein, C-hFc and His tag
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产品编号
KMH490
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别名
肿瘤坏死因子受体超家族成员21, DR6, CD358, BM 018, TNF receptor superfamily member 21
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
| Catalog Number | KMH490 |
| Alias | 肿瘤坏死因子受体超家族成员21, DR6, CD358, BM 018, TNF receptor superfamily member 21 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH490 Recombinant Human CD358/TNFRSF21 Protein, C-hFc and His tag contains the human TNFRSF21(Met1-Leu350) was expressed in Mammalian cells. |
| Molecular Name | TNFRSF21 |
| Product Introduction | TNFRSF21 (KMH490) 是肿瘤坏死因子受体超家族的一个成员,参与细胞凋亡与免疫调节。 |
| Molecular Weight | 95-100 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | ![]() |
| Purification | Affinity Purification |
| Uniprot ID | O75509 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Death receptor-6 (DR6), a member of the death domain-containing TNFR superfamily, is highly expressed in lymphoid tissues and regulated upon lymphocyte activation. Targeted disruption of DR6 results in enhanced CD4(+) T cell proliferation and T helper 2 differentiation in vitro. DR6 contains an extracellular region and an intracellular region; the intracellular region harbors a death domain that is critical for transduction of apoptotic signals. DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-κB and JNK. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Immobilized Human APP at 10 μg/mL (100 μL/well) can bind Human DR6 with a linearrange of 0.002-1.8 μg/mL. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环,以保持蛋白的稳定性。
可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。
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