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Recombinant Human CD358/TNFRSF21 Protein, C-hFc and His tag

Recombinant Human CD358/TNFRSF21 Protein, C-hFc and His tag

产品编号

KMH490

别名

肿瘤坏死因子受体超家族成员21, DR6, CD358, BM 018, TNF receptor superfamily member 21

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH490
Alias肿瘤坏死因子受体超家族成员21, DR6, CD358, BM 018, TNF receptor superfamily member 21
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH490 Recombinant Human CD358/TNFRSF21 Protein, C-hFc and His tag contains the human TNFRSF21(Met1-Leu350) was expressed in Mammalian cells.
Molecular NameTNFRSF21
Product IntroductionTNFRSF21 (KMH490) 是肿瘤坏死因子受体超家族的一个成员,参与细胞凋亡与免疫调节。
Molecular Weight95-100 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDO75509
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundDeath receptor-6 (DR6), a member of the death domain-containing TNFR superfamily, is highly expressed in lymphoid tissues and regulated upon lymphocyte activation. Targeted disruption of DR6 results in enhanced CD4(+) T cell proliferation and T helper 2 differentiation in vitro. DR6 contains an extracellular region and an intracellular region; the intracellular region harbors a death domain that is critical for transduction of apoptotic signals. DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-κB and JNK.
Endotoxin< 0.1 EU per ug
Protein FamilyCD molecule
Biological ActivityImmobilized Human APP at 10 μg/mL (100 μL/well) can bind Human DR6 with a linearrange of 0.002-1.8 μg/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
FAQ
  • 如何储存293F细胞中表达的蛋白?

    蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环,以保持蛋白的稳定性。

  • 如何提高293F细胞中的蛋白表达效率?

    可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。

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