Recombinant Human CD344/FZD4 Protein, C-hFc and His tag
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产品编号
KMH481
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别名
Frizzled受体4, Fz4, EVR1, FEVR, Fz 4, FzE4, GPCR, hFz4, CD344, FZD4S, frizzled class receptor 4
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH481 |
| Alias | Frizzled受体4, Fz4, EVR1, FEVR, Fz 4, FzE4, GPCR, hFz4, CD344, FZD4S, frizzled class receptor 4 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH481 Recombinant Human CD344/FZD4 Protein, C-hFc and His tag contains the human FZD4(37-180 aa) was expressed in Mammalian cells. |
| Molecular Name | FZD4 |
| Product Introduction | FZD4是Frizzled蛋白家族成员，调节细胞增殖、分化和神经发育。 |
| Molecular Weight | 58-60 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | Q9ULV1 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS, pH7.5 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Frizzled-4 (FZD4) is a Frizzled Receptor involved in mediating Wnt signaling that is widely expressed, particularly in heart, skeletal muscle, ovary, and fetal kidney. FZD4 functions as a ligand-receptor pair to control vascular development in the retina and inner ear. Fz4 expression may play a critical role in responses to Wnt signaling in the tumor microenvironment. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured by its binding ability in a functional ELISA. In a 100 µL reaction mixture containing biotinylated rmWnt-5a at 100 ng/mL and rhFrizzled-4/Fc Chimera dilutions at 0.1-2,000 ng/mL, the concentration of rhFrizzled-4/Fc Chimera that produces 50% of t |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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