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Recombinant Human CD334/FGFR4 Protein, C-hFc and His tag

Recombinant Human CD334/FGFR4 Protein, C-hFc and His tag

产品编号

KMH475

别名

成纤维生长因子受体4, TKF, JTK2, CD334, fibroblast growth factor receptor 4

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH475
Alias成纤维生长因子受体4, TKF, JTK2, CD334, fibroblast growth factor receptor 4
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH475 Recombinant Human CD334/FGFR4 Protein, C-hFc and His tag contains the human FGFR4(Leu22-Asp369) was expressed in Mammalian cells.
Molecular NameFGFR4
Product IntroductionFGFR4 (KMH475) 在细胞增殖和分化过程中起关键作用,参与肿瘤的发生。
Molecular Weight90-110 kDa.
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDP22455
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundFibroblast Growth Factors (FGFs) comprise a family of at least eighteen structurally realted proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family if type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1to -4 are known. Multiple forms of FGFR-1 to -3 are generated by alternative splicing of the mRNAs.
Endotoxin< 0.1 EU per ug
Protein FamilyCD molecule
Biological ActivityMeasured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.03-0.12 ng/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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