Recombinant Human CD334/FGFR4 Protein, C-hFc and His tag
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产品编号
KMH475
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别名
成纤维生长因子受体4, TKF, JTK2, CD334, fibroblast growth factor receptor 4
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规格
- 20ug
 - 50ug
 - 100ug
 - 200ug
 - 1mg
 
 
| Catalog Number | KMH475 | 
| Alias | 成纤维生长因子受体4, TKF, JTK2, CD334, fibroblast growth factor receptor 4 | 
| Size | 20ug, 50ug, 100ug, 200ug, 1mg | 
| Product Description | KMH475 Recombinant Human CD334/FGFR4 Protein, C-hFc and His tag contains the human FGFR4(Leu22-Asp369) was expressed in Mammalian cells. | 
| Molecular Name | FGFR4 | 
| Product Introduction | FGFR4 (KMH475) 在细胞增殖和分化过程中起关键作用,参与肿瘤的发生。 | 
| Molecular Weight | 90-110 kDa. | 
| Expression System | HEK293F Cells | 
| Species | Human | 
| Concentration | 联系销售经理获得最新批次的浓度 | 
| Purity | ≥95% | 
| SDS-PAGE | ![]()  | 
| Purification | Affinity Purification | 
| Uniprot ID | P22455 | 
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. | 
| Formulation | PBS | 
| Shipping Condition | This product is shipped on ice packs or dry ice. | 
| Background | Fibroblast Growth Factors (FGFs) comprise a family of at least eighteen structurally realted proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family if type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1to -4 are known. Multiple forms of FGFR-1 to -3 are generated by alternative splicing of the mRNAs. | 
| Endotoxin | < 0.1 EU per ug | 
| Protein Family | CD molecule | 
| Biological Activity | Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.03-0.12 ng/mL. | 
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 | 
							
							
							
							
						
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