| Catalog Number | KMH473 |
| Alias | 成纤维生长因子受体2, BEK, JWS, BBDS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR 1, CD332, K SAM, fibroblast growth factor receptor 2 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH473 Recombinant Human CD332/FGFR2 Protein, C-hFc and His tag contains the human FGFR2(Arg22-Glu377) was expressed in Mammalian cells. |
| Molecular Name | FGFR2 |
| Product Introduction | FGFR2 (KMH473) 在发育过程中参与细胞增殖和分化。 |
| Molecular Weight | 100-120 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | P21802 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Fibroblast Growth Factors (FGFs) comprise a family of at least eighteen structurally realted proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family if type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1to -4 are known. Multiple forms of FGFR-1 to -3 are generated by alternative splicing of the mRNAs. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.5-2 ng/mL. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |