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Recombinant Human CDW293/BMPR1B Protein, C-His tag

Recombinant Human CDW293/BMPR1B Protein, C-His tag

产品编号

KMH439

别名

骨形态发生蛋白受体1B型,ALK6, AMDD, BDA2, ALK 6, BDA1D, CDw293, bone morphogenetic protein receptor type 1B

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH439
Alias骨形态发生蛋白受体1B型,ALK6, AMDD, BDA2, ALK 6, BDA1D, CDw293, bone morphogenetic protein receptor type 1B
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH439 Recombinant Human CDW293/BMPR1B Protein, C-His tag contains the human BMPR1B(14-126 aa) was expressed in Mammalian cells.
Molecular NameBMPR1B
Product IntroductionBMPR1B (KMH439) 是骨形态发生蛋白 (BMP) 受体家族的一员,参与骨骼和软骨发育。
Molecular Weight20-30 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥90%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDO00238
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundBMPR1B (also known as ALK6) is a member of the transmembrane serine/threonine kinase that is the member of the bone morphogenetic protein (BMP) receptor, which is closely related to the activin receptors, ACVR1 and ACVR2. ALK6 is mainly involved in the endochondral bone formation and embryogenesis. ALK6 expressed in normal and cancerous prostate tissues and used in the endocrine therapy that given to the prostate cancer patients. BMPR1B receptor trafficking also play a significant role in FOP pathogenesis and used in human T-cell differentiation.
Endotoxin< 0.1 EU per ug
Protein FamilyCD molecule
Biological ActivityMeasured by its ability to inhibitrhBMP-4- induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 forthis effect is 0.5‑1.5 µg/mL in the presence of 30 ng/mL ofrhBMP- 4.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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