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Recombinant Human CD279/PDCD1 Protein, C-hFc and His tag

Recombinant Human CD279/PDCD1 Protein, C-hFc and His tag

产品编号

KMH428

别名

PDCD1, PD1, PD 1, CD279, SLEB2, hPD 1, hPD l, Hsle1, programmed cell death 1

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH428
AliasPDCD1, PD1, PD 1, CD279, SLEB2, hPD 1, hPD l, Hsle1, programmed cell death 1
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH428 Recombinant Human CD279/PDCD1 Protein, C-hFc and His tag contains the human PDCD1(Leu25-Thr168) was expressed in Mammalian cells.
Molecular NamePDCD1
Product IntroductionPDCD1调节免疫耐受性,防止过度的免疫反应和自体免疫疾病。
Molecular Weight60-70 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDQ15116
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationSupplied as solution form in 150 mM NaCl, 50 mM Tris-HCl, pH 7.5./ Lyophilized from 150 mM NaCl, 50 mM Tris-HCl, pH 7.5.
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundThis gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/cbackground developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Endotoxin< 0.1 EU per ug
Protein FamilyCD molecule
Biological ActivityImmobilized Recombinant Human PD-1 at 5 μg/mL (100 μL/well) can bind Recombinant Human PD-L1 with a linear range of 0.5-2 μg/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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