| Catalog Number | KMH414 |
| Alias | 肿瘤坏死因子受体超家族成员11A, FEO, OFE, ODFR, OSTS, PDB2, RANK, CD265, OPTB7, TRANCER, LOH18CR1, TNF receptor superfamily member 11a |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH414 Recombinant Human CD265/TNFRSF11A Protein, C-hFc and His tag contains the human TNFRSF11A(Gln29-Gly213) was expressed in Mammalian cells. |
| Molecular Name | TNFRSF11A |
| Product Introduction | TNFRSF11A参与破骨细胞的形成与骨骼的代谢调节。 |
| Molecular Weight | 60 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | Q9Y6Q6 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS, pH7.5 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | RANK (Receptor Activator of Nuclear Factor κ B), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. RANK ligand is found on the surface of stromal cells, osteoblasts, and T cells. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured by its ability to inhibit TRANCE-induced osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells. The ED50 forthis effect is 0.005‑0.035 µg/mL in the presence of 2 ng/mL of rmTRANCE. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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