Recombinant Human CD264/TNFRSF10D Protein, C-hFc and His tag
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产品编号
KMH413
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别名
肿瘤坏死因子受体超家族成员10D, DCR2, CD264, TRUNDD, TRAILR4, TRAIL R4, TNF receptor superfamily member 10d
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH413 |
| Alias | 肿瘤坏死因子受体超家族成员10D, DCR2, CD264, TRUNDD, TRAILR4, TRAIL R4, TNF receptor superfamily member 10d |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH413 Recombinant Human CD264/TNFRSF10D Protein, C-hFc and His tag contains the human TNFRSF10D(56-211 aa) was expressed in Mammalian cells. |
| Molecular Name | TNFRSF10D |
| Product Introduction | TNFRSF10D参与细胞凋亡的调节和免疫应答的启动。 |
| Molecular Weight | 60-70kD |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | Q9UBN6 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | TNF-related apoptosis-inducing ligand receptor 4 (TRAIL R4) is a decoy receptor that negatively regulate TRAIL-induced cytotoxicity by competing for ligand binding with TRAIL-R1 and TRAIL-R2.1 TRAIL R4 is expressed mainly on CD8+ and NK cells and induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4 contains partially truncated death domain and therefore is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured by its ability to inhibit TRAILmediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is 1.8-7.2 ng/mL in the presence of 20 ng/mL |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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如何判断蛋白是否有抗体反应性？
可以使用ELISA、Western blot或免疫沉淀等技术来检测蛋白与特定抗体的结合反应性。
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如何避免蛋白在纯化过程中的损失？
使用温和的纯化条件、优化缓冲液成分和减少操作步骤，可以有效减少蛋白的损失。
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