| Catalog Number | KMH387 |
| Alias | MUC1, EMA, MCD, PEM, PUM, KL 6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC 1, ADMCKD, ADMCKD1, CA 15 3, MUC 1/X, MUC1/ZD, MUC 1/SEC, mucin 1, cell surface associated |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH387 Recombinant Human CD227/MUC1 Protein, C-His tag contains the human MUC1(Met1-Ser380) was expressed in Mammalian cells. |
| Molecular Name | MUC1 |
| Product Introduction | MUC1是上皮细胞表面的糖蛋白，参与细胞保护和免疫调节。 |
| Molecular Weight | 50-55 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | P15941 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | MUC1 or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC1 is a proteoglycan with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. |
| Endotoxin | < 1.0 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured by its ability to increase beta-catenin levels in the cytoplasm and nucleus of HCT116 human colon adenocarcinoma cells. 0.01-1 ng/mL of Recombinant Human MUC-1 can effectively increase beta-catenin levels. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
取决于蛋白的稳定性和纯度。经过充分纯化的蛋白通常适用于X射线晶体学、NMR或冷冻电子显微镜等结构解析方法。
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