| Catalog Number | KMH381 |
| Alias | IL18受体A, ACPL, CD218b, IL 1R7, IL18RB, CDw218b, IL 1R 7, IL 18RAcP, IL 1RAcPL, IL 18Rbeta, IL 18R beta, interleukin 18 receptor accessory protein |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH381 Recombinant Human CD218B/IL18RAP Protein, C-His tag contains the human IL18RAP(20-356 aa) was expressed in Mammalian cells. |
| Molecular Name | IL18RAP |
| Product Introduction | IL18受体A在调节免疫反应及细胞激活中起到关键作用。 |
| Molecular Weight | 50-55 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | O95256 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Interleukin 18 receptor accessory protein, also known as IL18RAP, IL1R7 and CDw218b, is a single-pass type I membrane protein. It is member of the interleukin-1 receptor family. IL18RAP contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 TIR domain. IL18RAP is strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon. It is not expressed in any other tissue tested. IL18RAP is also strongly expressed in T-cells polarized with IL12 and specifically coexpressed with IL18R1 in Th1 cells. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured by its ability to inhibit the IL-18- induced response of KG‑1 human acute myelogenous leukemia cells in the presence of Recombinant Human IL‑18 R alpha /IL‑1 R5. The ED50 for this effect is 2‑6 µg/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
销售微信
官方公众号
0
