Recombinant Human CD218A/IL18R1 Protein, C-hFc and His tag_天津卡梅德科技发展有限公司

Recombinant Human CD218A/IL18R1 Protein, C-hFc and His tag

产品编号

KMH380

别名

IL-18受体1, IL18RA, IL1RRP, CDw218a, IL 1Rrp, IL 18Ralpha, IL18Ralpha2, IL 18R alpha, interleukin 18 receptor 1

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Catalog Number	KMH380
Alias	IL-18受体1, IL18RA, IL1RRP, CDw218a, IL 1Rrp, IL 18Ralpha, IL18Ralpha2, IL 18R alpha, interleukin 18 receptor 1
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	KMH380 Recombinant Human CD218A/IL18R1 Protein, C-hFc and His tag contains the human IL18R1(20-329 aa) was expressed in Mammalian cells.
Molecular Name	IL18R1
Product Introduction	IL18R1 (KMH380) 是与 IL-18 配对的受体，参与调节免疫反应，尤其是通过促使白细胞释放细胞因子。
Molecular Weight	80-100 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q13478
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	The interleukin-18 receptor 1 (IL-18R1) is a cytokine receptor of the immunoglobulin superfamily. IL18R1 is also known as IL-18Rα, CDw218a (cluster of differentiation w218a), IL-1Rrp, and IL-1R family member. IL-18R1 specifically binds to interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IL-18Rα is expressed on Th1 cells, NK cell subset, neutrophils and IL-12-stimulated tonsillar B cells. By itself, IL-18Rα binds IL-18 with low affinity and when complexed with IL-18Rβ chain binds IL-18 with high affinity. The proinflammatory cytokine IL-18 and its receptor complex play an important role in the innate and autoimmune responses.
Endotoxin	< 0.1 EU per ug
Protein Family	CD molecule
Biological Activity	Measured by its ability to inhibit the Recombinant Human IL-18 induced response on KG-1 human acute myelogenous leukemia cells in the presence of Recombinant Human IL-18 R beta /IL-1 R7 Fc Chimera . The ED50 for this effect is 0.400-4.00 μg/mL.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。