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Recombinant Human CD213A1/IL13RA1 Protein, C-His tag

Recombinant Human CD213A1/IL13RA1 Protein, C-His tag

产品编号

KMH377

别名

IL13受体A1, NR4, CT19, CD213A1, IL 13Ra, interleukin 13 receptor subunit alpha 1

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH377
AliasIL13受体A1, NR4, CT19, CD213A1, IL 13Ra, interleukin 13 receptor subunit alpha 1
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH377 Recombinant Human CD213A1/IL13RA1 Protein, C-His tag contains the human IL13RA1(Ala27-Thr343) was expressed in Mammalian cells.
Molecular NameIL13RA1
Product Introduction (KMH377) IL13RA1在调节免疫反应和过敏性反应中起到关键作用。
Molecular Weight62-70 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDP78552
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundInterleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1) is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL-13Ralpha1is essential for allergen-induced airway hyperreactivity and mucus hypersecretion.
Endotoxin< 0.1 EU per ug
Protein FamilyCD molecule
Biological ActivityImmobilized Human IL-13, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-13Ra1, His Tag with the EC50 of 2.8μg/ml determined by ELISA.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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