Recombinant Human CD209 Protein, C-His tag
-
产品编号
KMH373
-
别名
CD209分子, CDSIGN, CLEC4L, DC SIGN, DC SIGN1, CD209 molecule
-
规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH373 |
| Alias | CD209分子, CDSIGN, CLEC4L, DC SIGN, DC SIGN1, CD209 molecule |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH373 Recombinant Human CD209 Protein, C-His tag contains the human CD209(59-404 aa) was expressed in Mammalian cells. |
| Molecular Name | CD209 |
| Product Introduction | CD209是树突状细胞上的受体，参与病原识别和免疫反应。 |
| Molecular Weight | 40-50 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | Q9NNX6 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Human Dendritic Cell-specific ICAM-3 Grabbing Non-integrin (DC-SIGN)/CD29 is a member of the C-type lectin family. The canonical DC-SIGN/CD29 isoform is a 46 kDa, 44 amino acid (aa) type II transmembrane protein. The extracellular region contains a Ca2+-dependent carbohydrate-binding lectin domain. Multiple human DC-SIGN/CD29 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGN/CD29 is not well conserved between mouse and human, with the extracellular domain sharing only 63% aa identity. The DC-SIGN/CD29 lectin domain binds mannose oligosaccharides on pathogens including HIV as well as self glycoproteins including ICAMs. DC-SIGN/CD29 binds to butyrophilin 2A1 and this interaction can be blocked by HIV pp12. DC-SIGN/CD29 is expressed on dendritic cells (DC) and inflammatory macrophages and contributes to antigen presentation. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured by the ability of the immobilized protein to support the adhesion of ICAM-3 expressing CHO Chinese hamster ovary cells. When 5 x 10^4 cells/well are added to Recombinant Human DC_x005f_x001e_SIGN/CD209 Protein coated plates (5 μg/mL with 100 μL/w |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
-
表达的蛋白需要进行去盐处理吗？
如果蛋白的溶解性或活性受盐浓度的影响，通常会在纯化过程中使用透析或尺寸排阻层析去除盐分。
- 联系我们
- 电话：400-621-6806
- 手机：13116038708
- 邮箱：info@kmdbioscience.com
- 地址：天津市武清区国际企业社区A5栋
-
销售微信
-
官方公众号
-
400-621-6806 -
18630936064（微信同号） -
周一至周五 8:30-18:00 -
-
0
-
