Recombinant Human CD202B/TEK Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human CD202B/TEK Protein, His Tag

Recombinant Human CD202B/TEK Protein, His Tag

产品编号

KMH366

别名

TIE2, VMCM, GLC3E, TIE 2, VMCM1, CD202B, TEK receptor tyrosine kinase

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	TIE2, VMCM, GLC3E, TIE 2, VMCM1, CD202B, TEK receptor tyrosine kinase
Catalog Number	KMH366
Molecular Name	TEK
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	The molecularweight of the dimer is 25 kDa. The soluble receptor protein consists of thefull extracellular domain (Met1-Val73). TIE-1 (tyrosine kinase with Ig andEGF homology domains 1) and TIE2/TEK comprise a receptor tyrosine kinase(RTK) subfamily with unique structural characteristics: twoimmunoglobulin-like domains flanking three epidermal growth factor (EGF)-likedomains and followed by three fibronectin type III-like repeats in theextracellular region and a split tyrosine kinase domain in the cytoplasmicregion. These receptors are expressed primarily on endothelial andhematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE2 cDNA encodes a 1124 amino acidresidue precursor protein with an 18 residue putative signal peptide, a 727residue extracellular domain and a 354 residue cytoplasmic domain. Twoligands, angiopoietin 1 and angiopoietin 2, which bind TIE2 withhigh-affinity have been identified.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	81.95 kDa
Note	仅供科研使用

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