Recombinant Human CD201/PROCR Protein, C-His tag_天津卡梅德科技发展有限公司

Recombinant Human CD201/PROCR Protein, C-His tag

产品编号

KMH365

别名

PROCR, CCCA, EPCR, CCD41, protein C receptor

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KMH365
Alias	PROCR, CCCA, EPCR, CCD41, protein C receptor
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	KMH365 Recombinant Human CD201/PROCR Protein, C-His tag contains the human PROCR(Ser18-Ser210) was expressed in Mammalian cells.
Molecular Name	PROCR
Product Introduction	PROCR是内皮细胞受体，调节凝血过程并影响细胞的迁移。
Molecular Weight	36-40 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q9UNN8
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Endothelial Protein C Receptor (EPCR) is a Vitamin Kdependent Serine Protease that plays a major role in blood coagulation. Binding of Protein C to EPCR leads to the proteolytic activation of PAR1 (ProteaseActivated Receptor 1) on endothelial cells and subsequent upregulation of Protein Cinduced genes. EPCR is a type I transmembrane glycoprotein in the CD1/MHC family. It is expressed most strongly in the endothelial cells of arteries and veins in heart and lung. Membrane bound EPCR is released by metalloproteolytic cleavage to generate the soluble receptor. The extracellular domain of human and mouse EPCR shares approximately 61% amino acid sequence homology. EPCR plays an important role in augmenting Protein C activation by the ThrombinThrombomodulin complex and in regulating blood coagulation and inflammation. EPCR is found primarily on endothelial cells. Deletion of EPCR function results in embryonic death, at least in part due to placental thrombosis.
Endotoxin	< 0.1 EU per ug
Protein Family	CD molecule
Biological Activity	When human Activated Protein C (APC) is immobilized at 3 μg/mL, 100 μL/well, Recombinant Human EPCR binds with an ED50 of 1-5 μg/mL.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。