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Recombinant Human CD200 Protein, His Tag

Recombinant Human CD200 Protein, His Tag

产品编号

KMH364

别名

MRC, MOX1, MOX2, OX 2, CD200 molecule

规格
  • 50ug
  • 100ug
产品介绍
AliasMRC, MOX1, MOX2, OX 2, CD200 molecule
Catalog NumberKMH364
Molecular NameCD200
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundCD2, also known as OX-2, is a 45 kDa transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. CD2 is widely but not ubiquitously expressed. Its receptor (CD2R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD2. CD2 knockout mice are characterized by increased macrophage number and activation and are predisposed to autoimmune disorders. In T cells, CD2 functions as a costimulatory molecule independent of the CD28 pathway. Several viruses encode CD2 homologs which are expressed on infected cells during the lytic phase. Like CD2 itself, viral CD2 homologs also suppress myeloid cell activity, enabling increased viral propagation.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight25.52 kDa
Note仅供科研使用

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