| Catalog Number | KMH337 |
| Alias | KIR3DS1KIR G1, NKAT10, CD158E2, NKAT 10, KIR 123FM, killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH337 Recombinant Human CD158E2/KIR3DS1 Protein, C-hFc and His tag contains the human KIR3DS1(22-340 aa) was expressed in Mammalian cells. |
| Molecular Name | KIR3DS1 |
| Product Introduction | (KMH337) KIR3DS1是自然杀伤细胞的受体，调节免疫系统的活性。 |
| Molecular Weight | 75-90 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | Q14943 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | KIR3DS1(3DS1, CD158e2) is a type I transmembrane protein that belongs to the killercell Ig-like receptor (KIR) family. KIRs are expressed on CD56 dim NK cellsand T cell subsets where they differentiate normal from abnormal cells, and regulateeffector functions in the innate immune system. KIRs are named for the numberof Ig-like domains (2D or 3D) in the extracellular domain(ECD), and whether theyhave long or short (L, S) cytoplasmic tails. Like other activating KIRs, KIR3DS1has a short cytoplasmic tail and a positively charged amino acid (aa) withinthe transmembrane domain that interacts with the ITAM-bearing signalingadaptor, DAP12. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured by its ability to bind HLA on MDA‑MB‑231 human breast cancer cells. The ED50 forthis effect is 0.03-0.18 μg/mL |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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