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Recombinant Human CD155/PVR Protein, C-hFc and His tag

Recombinant Human CD155/PVR Protein, C-hFc and His tag

产品编号

KMH328

别名

脊髓灰质炎病毒受体, PVS, HVED, CD155, NECL5, TAGE4, Necl 5, PVR cell adhesion molecule

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH328
Alias脊髓灰质炎病毒受体, PVS, HVED, CD155, NECL5, TAGE4, Necl 5, PVR cell adhesion molecule
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH328 Recombinant Human CD155/PVR Protein, C-hFc and His tag contains the human PVR(Asp28-Asn343) was expressed in Mammalian cells.
Molecular NamePVR
Product IntroductionPVR (KMH328) 作为免疫细胞的受体,参与免疫反应的调节。
Molecular Weight95-105 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDP15151
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundCD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.
Endotoxin< 0.1 EU per ug
Protein FamilyCD molecule
Biological ActivityImmobilized Human CD155 at 2 μg/mL (100 μL/well) can bind Human CD96 with a linear range of 0.1-76 ng/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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