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Recombinant Human CD153/TNFSF8 Protein, Fc Tag

Recombinant Human CD153/TNFSF8 Protein, Fc Tag

产品编号

KMH326

别名

CD153, CD30L, CD30LG, TNLG3A, TNF superfamily member 8

规格
  • 50ug
  • 100ug
产品介绍
AliasCD153, CD30L, CD30LG, TNLG3A, TNF superfamily member 8
Catalog NumberKMH326
Molecular NameTNFSF8
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundThe CD3 ligand is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily. CD3L is expressed on the cell surface of activated T cells, B cells, and monocytes. Recombinant CD3L has been shown to co-stimulate T cells and to act as a mitogen for Hodgkin"s disease derived cell lines. The receptor for CD3L, CD3/TNFRSF8/CD153, is a type I cytokine receptor that is highly expressed by activated T cells, Hodgkin and Reed- Sternberg (H-RS) cells, and anaplastic large cell lymphoma cells. CD3 ligation by CD3L mediates pleiotropic effects including cell proliferation, activation, differentiation and cell death by apoptosis.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight43.92 kDa
Note仅供科研使用

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