Recombinant Human CD153/TNFSF8 Protein, N-His
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产品编号
KMH326
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别名
TNFSF8, CD153, CD30L, CD30LG, TNLG3A, TNF superfamily member 8
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH326 |
| Alias | TNFSF8, CD153, CD30L, CD30LG, TNLG3A, TNF superfamily member 8 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH326 Recombinant Human CD153/TNFSF8 Protein, N-His contains the human TNFSF8(63-234 aa) was expressed in Mammalian cells. |
| Molecular Name | TNFSF8 |
| Product Introduction | (KMH326) TNFSF8是TNF超家族的一员，调节T细胞的功能，参与免疫反应。 |
| Molecular Weight | 25-45 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | P32971 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | The CD3 ligand is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily. CD3L is expressed on the cell surface of activated T cells, B cells, and monocytes. Recombinant CD3L has been shown to co-stimulate T cells and to act as a mitogen for Hodgkin"s disease derived cell lines. The receptor for CD3L, CD3/ TNFRSF8/CD153, is a type I cytokine receptor that is highly expressed by activated T cells, Hodgkin and Reed- Sternberg (H-RS) cells, and anaplastic large cell lymphoma cells. CD3 ligation by CD3L mediates pleiotropic effects including cell proliferation, activation, differentiation and cell death by apoptosis. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured by its ability to stimulate IL-6 secretion by HDLM human Hodgkin’s lymphoma cells. The ED50 forthis effect is 8-48 ng/mL in the presence of 10 µg/mL of a cross-linking antibody, Mouse AntipolyHistidine Monoclonal Antibody. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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