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Recombinant Human CD130/IL6ST Protein, C-hFc and His tag

Recombinant Human CD130/IL6ST Protein, C-hFc and His tag

产品编号

KMH306

别名

IL6受体, CD130, GP130, HIES4, CDW130, IL 6RB, sGP130, interleukin 6 signal transducer

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH306
AliasIL6受体, CD130, GP130, HIES4, CDW130, IL 6RB, sGP130, interleukin 6 signal transducer
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH306 Recombinant Human CD130/IL6ST Protein, C-hFc and His tag contains the human IL6ST(ELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEI) was expressed in Mammalian cells.
Molecular NameIL6ST
Product Introduction (KMH306) IL6ST参与免疫反应,调节免疫细胞的功能和炎症反应。
Molecular Weight120-150 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDP40189
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundGlycoprotein 13 (also known as gp13, IL6ST, IL6-beta or CD13) is a transmembrane protein which is the founding member of the class of tall cytokine receptors. It forms one subunit of type I cytokine receptors within the IL-6 receptor family. It is often referred to as the common gp13 subunit, and is important for signal transduction following cytokine engagement. Gp13 signals are mediated by tyrosine kinases of the JAK family and by their binding partners, transcription factors of the STAT family. Gp13 signaling is very important for osteoblast function and calcium homeostasis.
Endotoxin< 0.1 EU per ug
Protein FamilyCD molecule
Biological ActivityMeasured by its ability to inhibit IL-6-dependent proliferation of the 7TD1 mouse hybridoma cells in the presence of Recombinant Human IL-6 R alpha . The ED50 for this effect is 0.65-6.5 ng/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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